Navi Mumbai based Stem Rx Bioscience Solutions Pvt Ltd effectively restored the eyesight of a 58-year-old man with age-connected macular degeneration (AMD) by cell-based therapy.
Loss of vision brought on by AMD can be restored by making use of the patient’s personal stem cells to repair broken tissue and remedy the illness.
“Loss of vision has a huge impact on a person’s life, but many of the disorders that cause blindness are currently difficult or impossible to treat,” Informed Dr. Pradeep Mahajan, Regenerative Medicine Researcher, StemRx Bioscience Solutions Pvt. Ltd., Mumbai.
AMD is a situation that impacts central vision. It impacts the macula, which is the light-sensitive tissue at the back of the eye, due to which the capability to clearly see objects that are straight ahead gets impacted. AMD happens frequently in the elderly, commonly soon after 50 years of age, due to gradual thinning of the macula or even due to abnormal development of blood vessels below the retina.
The patient, Shyam Karanje, was diagnosed with cataract in October 2015. Few more investigations revealed that there was an abnormal membrane development in his suitable eye, which implies that he had new, abnormal blood vessels expanding in his eye. Thus, he was ultimately diagnosed with AMD and this was the cause for his diminishing vision. Despite many injections of a drug to cease the development of the blood vessels and stop leakage, he did not attain any improvement. He was subsequently advised a sort of laser therapy and eventually surgery, but was informed that the results of the procedures in restoring his vision was unpredictable. Karanje lost pretty much 75% of his vision because diagnosis.
Dr. Mahajan explained, “After studying the history of the patient, we decided to locally administer cells via eye drops. We planned 3 to 4 sessions of treatment, with each session lasting 3 days. The stem cell vials were regularly provided to the patient to continue the treatment. There was no surgical procedure involved. The patient was instructed to use the cells as eye drops. Neutraceuticals were advised for supportive care.”
He additional added, “Cell-based therapy provides new, healthy specialized cells and initiates healing and replacement of damaged cells in the eye. Stem cells have several other functions by which they maintain homeostasis or balance in different organs, including the eye. Normally, stem cells in the eye (and other organs) periodically renew themselves and generate new cells; however, with age this production slows down. Moreover, co-existing conditions like diabetes or any blood vessel-related conditions can further affect the normal functions of stem cells. Thus, conditions like AMD occur.”
Therefore, delivering healthier cells will support in regenerating the lost tissues as effectively as produce a healthier atmosphere in the eye that aids in regaining lost functions/vision.
After finishing all sessions of the remedy, the patient stated, “I used to face problems in performing my daily activities due to weak eyesight. For example, while reading, looking at or searching for household things, walking, and so on, I was unable to clearly see what was in front of me. Due to this, I needed assistance for several day-to-day activities. However, after the treatment, I gradually started noticing improvement in my vision. Even the doctors were positive about the changes. During a check-up, I was able to read the first line in the chart, which was not possible before.”
Later, a retina specialist also confirmed the improvement and recommended routine adhere to-up alone. The patient was told that he does not will need any additional remedy as his situation is steady and he is displaying continual improvement in vision.